Dr. Stella A. Safo is a Ghanaian-American HIV primary care physician, public health practitioner, and nationally recognized leader in equitable health system design. Her career reflects an unwavering commitment to the belief that health is a human right, and that meaningful change in healthcare requires courage, collaboration, and a deep sense of purpose. Through her clinical practice, executive leadership roles, and advocacy, she has consistently worked to redefine what effective, compassionate, and justice-centered healthcare looks like for communities across the United States and globally.
From a young age, Dr. Safo’s lived experiences shaped her understanding of inequity and inspired her pursuit of medicine as a vehicle for social change. She went on to complete her undergraduate, medical, and public health education at Harvard University, earning her MPH as a Zuckerman Fellow at the Harvard T.H. Chan School of Public Health. Her training culminated in Montefiore’s Primary Care and Social Medicine residency, followed by a fellowship through the HIV Medicine Association, where she honed her expertise in HIV care and deepened her commitment to marginalized communities whose health outcomes are influenced by social determinants and systemic barriers.
Early in her career, Dr. Safo became known for her ability to unite clinical insight with strategic innovation. As Senior Medical Director for Clinical Transformation at the Mount Sinai Health System, she led the redesign of more than 50 primary care practices, working across a complex, eight-hospital network to build care delivery models that were proactive, patient-centered, and sustainable under changing payment structures. Her leadership style—rooted in transparency, empathy, and data-driven decision-making—helped strengthen care coordination and inspired a culture of continuous improvement among physicians and frontline staff.
Her impact expanded nationally when she joined Premier Inc. as Chief Clinical Transformation Officer, where she oversaw the Applied Science and Implementation Research teams. In this role, she guided researchers in leveraging one of the nation’s largest healthcare datasets to identify and translate innovative clinical findings into practical models that improved patient care across U.S. health systems. She led national collaboratives, supported organizational partners through system redesign, and championed equity-focused research that lifted the voices and experiences of vulnerable patient populations.
In 2021, fueled by her growing determination to center equity in every aspect of healthcare, Dr. Safo founded Just Equity for Health (JEH), a healthcare improvement company dedicated to integrating justice principles into care model design, organizational strategy, and educational initiatives. Through JEH and her consulting work, she partners with health systems, public health institutions, institutions, and government entities to examine and redesign structures that contribute to societal inequities. Her approach reflects a deep respect for community expertise, prioritizing solutions that are both culturally informed and operationally feasible.
Her leadership extends beyond organizational transformation to national advocacy. As a founding member of Equity Now at Mount Sinai, Civic Health Alliance, and the Coalition to Advance Antiracism in Medicine, she has been a powerful voice in calling out structural discrimination and demanding accountability. In 2019, she joined colleagues in filing a federal lawsuit against Mount Sinai for gender, race, and age discrimination—an act of courage that led to the establishment of New York City’s Gender and Racial Equity Advisory Committee. This advocacy solidified her role as a changemaker willing to hold institutions to higher standards of justice.
A deeply committed educator, Dr. Safo holds appointments as Assistant Professor of Medicine and Medical Education at Mount Sinai and as the Director of the Social Medicine Curriculum and Adjunct Faculty at Montefiore Health System. She has trained countless medical students, residents, and fellows, inspiring future leaders to consider compassion, equity, and community partnership foundational to their clinical practice. Her ability to bridge scholarship and real-world implementation has made her a respected mentor and thought leader in academic medicine.
As a practicing HIV and LGBTQ+ clinician at Mount Sinai’s Institute for Advanced Medicine and the Callen-Lorde Community Health Center in NYC, Dr. Safo maintains a direct connection to patient care. Her clinical work remains a grounding force, reminding her of the human experiences that health systems are meant to support. This balanced perspective—spanning executive leadership, public health, system design, and frontline care—strengthens her unique ability to transform healthcare with both precision and heart.
Her commitment to community empowerment has led to the creation of initiatives such as Thriving in the Last Mile, supporting Black and minority physicians facing workforce discrimination, and the Green Book for Health, which provides guidance to ensure safe, affirming care experiences for Black healthcare users. Her global work, including roles in Ghana and Bangladesh through Praava Health, reflects her belief that equitable healthcare solutions must transcend borders.
Dr. Safo’s contributions have been recognized through publications in leading journals such as JAMA Network Open, AIDS and Behavior, Harm Reduction Journal, and Annals of Global Health. She has appeared on CNN, MSNBC, CBS, Yahoo Finance, and Cheddar, and her advocacy has been covered in The New York Times, The Wall Street Journal, and the Associated Press. In 2020, Modern Healthcare honored her as one of the Minority Clinicians to Watch, acknowledging her growing influence and national impact.
Across every dimension of her work—clinical, academic, entrepreneurial, and advocacy-driven—Dr. Stella Safo remains steadfast in her mission to create a healthcare landscape where dignity, equity, and compassion guide every decision. Her leadership reflects not only expertise and innovation, but a profound sense of responsibility to communities whose wellbeing has long been undervalued. She continues to build systems that honor humanity, elevate diverse voices, and expand access to the care every person deserves.
Character:
Dr. Safo demonstrates character through her unwavering commitment to equity, even when doing so requires challenging powerful institutions. She consistently centers patients and communities, making decisions rooted in empathy and justice. Her courage in advocacy reflects a deep sense of integrity that guides her leadership across all environments.
Knowledge:
She embodies knowledge through her extensive clinical, academic, public health, and operational expertise cultivated over fifteen years of practice, research, and leadership. She integrates data, lived experience, and interdisciplinary insight to build forward-thinking solutions to complex healthcare challenges. Her global and domestic perspectives allow her to navigate systems with exceptional depth and clarity.
Strategic:
Dr. Safo brings strategic excellence to organizations by uniting vision with pragmatic implementation, ensuring that high-level goals translate into lasting operational change. She designs care models that anticipate future needs while addressing present inequities. Her ability to align diverse stakeholders demonstrates her sophisticated approach to system-wide transformation.
Communication:
An impactful communicator who translates complex health concepts into clear, compelling messages tailored to diverse audiences. She uses her platform to advocate for justice, mobilize communities, and educate medical professionals with clarity and purpose. Her national media presence and teaching roles further highlight her ability to inspire and inform through thoughtful dialogue.


