Dominick Southmayd is an accomplished executive with over 25 years of experience in engineering, operations, and strategic leadership within the manufacturing, consumer products, and biopharma industries. With a Master’s degree in Chemical Engineering from Syracuse University, Dominick has demonstrated a commitment to driving operational excellence, cost reduction, and compliance across diverse sectors. His career journey has included key roles at top organizations, such as Thermo Fisher Scientific, AstraZeneca, Lonza, and WR Grace, where he has led high-stakes initiatives that emphasize process optimization, quality control, and safety management.
As the Director of Engineering and Facilities at Thermo Fisher Scientific, Dominick led the startup of a viral vector manufacturing operation, overseeing 55+ team members across engineering, process, automation, and validation. Managing operational budgets over $20 million and capital expenses exceeding $5 million, he played a pivotal role in setting strategic objectives that optimized site efficiency and supported P&L development. His leadership on the Site Leadership Team and in cross-functional collaborations has been instrumental in achieving strategic growth and operational continuity.
Dominick’s role as Senior Director of Engineering and Facilities at Akron Biotechnology involved the successful establishment of a GMP-compliant manufacturing facility. His expertise in project management and regulatory compliance facilitated the development of critical operational systems like CMMS and SAP, positioning Akron as a key player in microbial processing. His extensive experience includes building collaborative relationships with state and local economic development departments to secure investment and operational incentives, further underscoring his business acumen.
Throughout his career, Dominick has driven significant achievements in cost reduction, quality enhancement, and organizational turnaround. As Director of Engineering and Facilities at Macrogenics, he managed project engineering and facility operations for a complex spanning 220,000 square feet, delivering operational efficiencies and overseeing an annual budget of $18 million. His contributions to high-profile projects in biopharma have enhanced the performance of critical functions, from clinical manufacturing to commercial operations, demonstrating his commitment to both technical excellence and strategic impact.
Beyond the corporate sphere, Dominick has built and managed his own ventures, including a real estate business (TMG LLC) and a technical consulting firm (316 Engineering Solutions). His entrepreneurial success reflects his versatility and ability to apply engineering and operations expertise to drive growth and sustainability across multiple domains. As Co-Owner of TMG LLC, he developed a real estate portfolio valued at over $1.5 million, managing project development, maintenance, and resale strategies to achieve consistent financial performance.
Dominick’s early career at companies such as W.R. Grace and Millennium Chemical laid the groundwork for his expertise in chemical engineering, where he developed competencies in process design, production planning, and regulatory compliance. His work at Westinghouse Savannah River Site further refined his skills in facility startup, safety systems, and project management, giving him a solid foundation in managing complex, high-stakes environments.
An adept communicator and collaborative leader, Dominick excels at building and leading cross-functional teams focused on customer requirements, KPIs, and Environmental Health and Safety (EHS) standards. His proficiency in Lean Six Sigma, Total Quality Management (TQM), and continuous improvement methodologies has consistently resulted in substantial improvements in operational efficiency and team performance. His dedication to fostering a culture of innovation and accountability has positioned him as a trusted leader capable of driving sustainable results.
Currently, Dominick is exploring new opportunities to leverage his extensive experience in engineering management, operations, and strategic planning. His passion for mentorship and organizational development, coupled with his technical expertise and business insight, make him a valuable asset to any organization seeking to enhance operational performance and foster long-term growth.
Character: Dominick Southmayd is a dedicated and resilient leader known for his commitment to safety, compliance, and fostering team collaboration across all levels.
Knowledge: With over 25 years in engineering, operations, and manufacturing, Dominick brings deep expertise in biopharma, process optimization, and regulatory compliance across diverse industries.
Strategic: Dominick is a results-oriented strategist, adept at aligning operational improvements with organizational goals to drive growth, cost reduction, and efficiency gains.
Communication: Dominick is an effective communicator who builds cohesive teams, ensuring alignment on project goals and fostering a culture of continuous improvement and accountability.
